当前,虽然对癫痫状态(SE)的治疗有了进步,但少数病例经用常规、标准的治疗仍然无效。这类顽固的癫痫持续状态(RSE 患者的死亡率,)各家报道不一,分别为0%、31%、43%、及77%;死亡率的高低取决于SE 的时间及其潜在原因。一组小儿死亡率为18%,而新发现的神经系统损害高达63%。本文报告一例RSE 经手术治疗成功的患者。患儿男,9.8岁,右利手,妊娠史不详。出生后一周出现第一次抽搐,六个月龄时第二次抽搐。入院前2月抽搐加重,每小时抽搐1～2次,发作前有明显的先兆。大部分为局限性发作,有时为全身强直性阵挛性抽搐,每次持续1～3分钟。经用多种抗癫痫药物治疗均无效。入院前4天患儿处于癫痫持续状态,使用戊巴比妥后患儿进入昏迷状态。脑电图显示连续高波幅、慢波;于右大脑半球常见暴发性尖波。静脉滴注戊巴比妥时,暴发性波则被抑制,如果减少 At present, although progress has been made in the treatment of epileptic conditions (SE), a small number of cases are still ineffective with conventional, standard treatment. The persistent state of epilepsy (mortality in RSE patients) varied from 0%, 31%, 43%, and 77%, respectively; the level of mortality was dependent on the time of the SE and its underlying causes. A group of children has a 18% mortality rate, while newly discovered neurological damage is as high as 63%. This article reports a successful case of RSE surgically treated. Children male, 9.8 years old, right hand, pregnancy history unknown. The first convulsion occurs one week after birth and the second convulsions at six months of age. Convulsions increased in February before admission, convulsions per hour 1 or 2 times before the onset of significant signs. Mostly localized attacks, sometimes tonic for generalized tonic clonic seizures, each lasting 1 to 3 minutes. After using a variety of antiepileptic drugs were ineffective. Four days before admission, the child was in status epilepticus and the child was unconscious after using pentobarbital. EEG shows continuous high amplitude, slow wave; common in the right cerebral hemisphere spike. When intravenous drip pentobarbital, fulminant waves are suppressed, if reduced