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目前 ,由于碳酸钙具有价格低廉 ,副作用较小等特点 ,已被国内广泛地用作补钙剂原料 ,中国药典也已将碳酸钙作为补钙原料收载[1,2 ] 。但是碳酸钙为不溶于水的无机化合物 ,通过在胃中溶解后吸收 ,长期使用可影响消化功能 ,为提高碳酸钙的生物利用度和减少不良反应 ,在处方中加入
At present, calcium carbonate has been widely used as a raw material for calcium supplement because of its low price and less side effects. The Chinese Pharmacopoeia also contains calcium carbonate as a calcium supplement [1,2]. However, calcium carbonate is a water-insoluble inorganic compound, which is absorbed by the stomach and absorbed after long-term use, and can affect digestion function. In order to improve the bioavailability of calcium carbonate and reduce adverse reactions,