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目的:探讨咪喹莫特乳膏+卡介菌多糖核酸治疗扁平疣疗效及安全性。方法:分析我院收治的扁平疣病人资料,将单一药物治疗分为对照组,接受联合治疗分为观察组。比较2组临床疗效、T细胞亚群情况及不良反应。结果:观察组(4周、6周、8周)治疗有效率高于对照组(P<0.05)。观察组T细胞亚群情况优于对照组(P<0.05)。观察组不良反应率高于对照组(P<0.05)。结论:咪喹莫特乳膏联合卡介菌多糖核酸治疗扁平疣疗效较佳,但临床安全性差,需做好预后工作。
Objective: To investigate the efficacy and safety of imiquimod cream + BCG polysaccharide nucleic acid in the treatment of flat warts. Methods: Analysis of flat wart patients admitted to our hospital, the single drug treatment is divided into control group, receiving combined treatment was divided into observation group. The clinical efficacy, T cell subsets and adverse reactions in the two groups were compared. Results: The effective rate of treatment in observation group (4 weeks, 6 weeks and 8 weeks) was higher than that of control group (P <0.05). The observation group T cell subgroups better than the control group (P <0.05). Adverse reaction rate in observation group was higher than that in control group (P <0.05). Conclusion: Imiquimod cream combined with BCG polysaccharide nucleic acid treatment of flat warts better efficacy, but poor clinical safety, the need for good prognosis.