Diabetes mellitus (DM) peripheral nerve lesion (PNL) is a common chronic complication of DM. Its incidence accounts for 40%-60% of DM patients. Since electro-physiological examination was developed, its detective rate has reached as high as around 85%(1). It is a disease that seriously affects the patients′ quality of life.Therefore, our hospital used Ziyin Yangxue Tongluo recipe (滋阴养血通络方, ZYYXTL)in treating 31 patients suffering from DMPNL from April to October 1998, and at the same time nimodipine capsule was used to treat 30 patients of the same disease as the control group. Here the clinical study is reported as follows.