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目的评价高频微探头内镜超声检查(EUS)在胃癌TN分期中的价值。方法胃癌患者98例均行高频微探头内镜超声检查,了解肿瘤侵犯深度、局部淋巴结转移情况,采用外科手术后病理为金标准进行对照,了解EUS在胃癌TN分期中的准确性。结果(1)EUS对TN分期阳性诊断正确率分别为88.78%,66.33%;(2)EUS对TN分期诊断过深率分别为6.12%,0(P<0.05);过浅率分别为5.10%,33.67%(P<0.05);(3)EUS对T分期有较高的敏感性(87.10%～100%)和特异性(81.25%～100%),阳性预测值83.33%～100%,阴性预测值94.37%～100%;EUS对N分期阳性诊断的敏感性、特异性、阳性及阴性预测值分别为52.17%、100%、100%、46.77%。结论高频微探头内镜超声检查对判断肿瘤侵犯深度的诊断(T分期)较准确,对判断局部淋巴结转移的诊断(N分期)有一定价值。
Objective To evaluate the value of endoscopic ultrasonography (EUS) of high frequency microprobe in TN staging of gastric cancer. Methods 98 patients with gastric cancer underwent endoscopic ultrasound examination of high frequency microprobe to understand the depth of tumor invasion, local lymph node metastasis, using surgical pathology as the gold standard for control, to understand the accuracy of EUS in TN staging of gastric cancer. Results (1) The correct diagnostic accuracy of EUS for TN staging was 88.78% and 66.33% respectively. (2) The over-depth rates of EUS TN staging were 6.12% and 0 (P <0.05) respectively; the superficial rates were 5.10% , 33.67% respectively (P <0.05). (3) EUS had higher sensitivity (87.10% ~ 100%) and specificity (81.25% ~ 100%) for T stage, with a positive predictive value of 83.33% ~ 100% The predictive value was 94.37% ~ 100%. The sensitivity, specificity, positive predictive value and negative predictive value of EUS were 52.17%, 100%, 100% and 46.77% respectively. Conclusions The endoscopic ultrasonography of the high-frequency microprobe is more accurate in diagnosing the depth of tumor invasion (T stage), which is of value in judging the diagnosis of Nodal lymph node metastasis (N stage).