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目的探讨心脏再同步化治疗(CRT)患者双室同步起搏与左心室内同步化的相关性。方法行CRT患者128例,按术后心电图特点分为双室同步起搏组(78例)和双室非同步起搏组(50例)。随访1年,多普勒超声心动图观察测定Ts-SD、Te-SD在不同组中的变化差异,评价左心室内同步化的变化。结果 1双室同步起搏组植入前较植入后Ts-SD〔(45±9)ms vs.(33±7)ms,P<0.05〕、Te-SD〔(41±8)ms vs.(31±8)ms,P<0.05〕有统计学意义;2单因素方差分析示Ts-SD、Te-SD、LVESV比较有统计学意义(P<0.05);3多因素分析示双室同步起搏与Ts-SD(B=-0.052,P=0.000)、Te-SD(B=-0.032,P=0.032)呈线性相关;4双室同步化起搏与Ts-SD行Pearson分析具有相关性(r=-0.933,P=0.000),Ts-SD呈负相关。结论经CRT治疗双室同步起搏组较双室非同步起搏组术后随访过程中左心室内协调性得到改善更加显著。
Objective To investigate the correlation between biventricular synchronized pacing and left ventricular systolic synchrony in patients with cardiac resynchronization therapy (CRT). Methods 128 cases of CRT patients were divided into two groups according to postoperative ECG characteristics: double-chamber synchronous pacing group (78 cases) and double-chamber asynchronous pacing group (50 cases). After one year of follow-up, Doppler echocardiography was used to measure the changes of Ts-SD and Te-SD in different groups and evaluate the changes of left ventricular synchronization. Results Compared with Ts-SD 〔(45 ± 9) ms vs. (33 ± 7) ms, P <0.05〕, Te-SD 〔(41 ± 8) ms vs (31 ± 8) ms, P <0.05] .2 The one-way ANOVA showed that there was a significant difference between Ts-SD, Te-SD and LVESV Synchronous pacing was linearly correlated with Ts-SD (B = -0.052, P = 0.000) and Te-SD (B = -0.032, P = 0.032) Correlation (r = -0.933, P = 0.000), Ts-SD was negatively correlated. Conclusion The improvement of left ventricular coordination in CRT-treated double-chamber synchronized pacing group was more significant than that of double-chamber asynchronous pacing group after follow-up.