癫痫是慢性反复发作性短暂脑功能失调综合征,以脑神经元异常放电引起反复痫性发作为特征。癫痫是神经系统常见疾病之一,病因极其复杂,中枢神经系统病变影响结构或功能等,如局灶性或弥漫性脑部疾病均可引起。对于癫痫的治疗,除了病因治疗、外科治疗外,最重要的是控制发作,目前以药物治疗为主。丙戊酸钠(sodium valproic acid,VPA)作为临床一线抗癫痫药物广泛用于全身性发 Epilepsy is a chronic recurrent episode of transient brain dysfunction syndrome characterized by recurrent seizures caused by abnormal firing of cerebral neurons. Epilepsy is one of the common diseases of the nervous system, the etiology is extremely complex, the central nervous system lesions affect the structure or function, such as focal or diffuse brain disease can cause. For the treatment of epilepsy, in addition to the cause of treatment, surgical treatment, the most important thing is to control the attack, the current drug-based. Sodium valproic acid (VPA) is widely used as a systemic first-line antiepileptic drug in generalized