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目的观察丙泊酚与米达唑仑在无痛胃镜麻醉时对心率、血压、氧饱和度的影响。方法芬太尼20μg/次+丙泊酚23 mg/(kg.次);两组麻醉药物选择芬太尼40μg/次+米达唑仑0.4~0.5 mg/(kg.次)。结果一组中有80%的病人虽然心律、血压、氧饱和度均下降,但不危及生命,均在3~5 min内自行恢复;而20%因心律、血压、氧饱和度严重下降,并威胁到生命安全而进行干预治疗或者停止手术。两组中虽然血压、心律、氧饱和度有所下降,但均在安全范围,不用干预治疗,均顺利完成手术。结论芬太尼+丙泊酚虽在无痛胃镜中具有显效快、清醒快的特点,是无痛胃镜的首选方式之一,但对慢性气管炎、肺气肿、肥胖及65岁以上的老人选择芬太尼+米达唑仑更安全。
Objective To observe the effects of propofol and midazolam on heart rate, blood pressure and oxygen saturation during painless gastroscopic anesthesia. Methods Fentanyl 20μg / times + propofol 23 mg / (kg); the two groups of anesthetic drugs fentanyl 40μg / times + midazolam 0.4 ~ 0.5 mg / (kg times). Results 80% of the patients in one group had self-recovery within 3 ~ 5 min though their heart rhythm, blood pressure and oxygen saturation decreased, but they did not endanger their life. 20% of the patients had a serious decrease of heart rate, blood pressure and oxygen saturation Threaten the safety of life to intervene the treatment or stop the operation. Although blood pressure, heart rate and oxygen saturation decreased in both groups, they were all in the safe range without intervention, and the operation was successfully completed. Conclusion Fentanyl + propofol is one of the preferred methods of painless gastroscopy, although it has the characteristics of rapid onset and rapid awakening in painless gastroscopy. However, it is one of the preferred methods for painless gastroscopy. However, it is not effective for chronic bronchitis, emphysema, obesity and elderly over 65 years Select fentanyl + midazolam safer.