论文部分内容阅读
目的观察阿司匹林加氯吡格雷对不稳定型心绞痛的疗效。方法97例不稳定心绞痛患者分为治疗组及对照组,治疗组在应用阿司匹林及低分子肝素基础上加用氯吡格雷,观察1周内心绞痛控制情况及1个月内临床心血管事件(包括心绞痛复发、急性心肌梗死、心源性猝死)及出血并发症情况。结果1周内中、高危治疗组有效控制心绞痛发作及高危治疗组1个月内控制临床心血管事件明显优于对照组。结论阿司匹林加氯吡格雷明显减少不稳定型心绞痛患者临床心血管事件的发生率,严重出血并发症无明显增加。
Objective To observe the effect of aspirin and clopidogrel on unstable angina pectoris. Methods 97 patients with unstable angina pectoris were divided into treatment group and control group. The treatment group was given clopidogrel on the basis of aspirin and LMWH. The control of angina pectoris within 1 week and the clinical cardiovascular events within 1 month (including Angina recurrence, acute myocardial infarction, sudden cardiac death) and bleeding complications. Results In 1 week, the control of angina pectoris and the control of clinical cardiovascular events within 1 month in high-risk treatment group were significantly better than those in control group. Conclusion Aspirin plus clopidogrel significantly reduced the incidence of clinical cardiovascular events in patients with unstable angina pectoris, with no significant increase in severe bleeding complications.