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[目的]探讨脂肪肝患者血脂、血液流变学的特征以及两者之间的关系。[方法]比较310例脂肪肝患者和246例正常对照的血脂和血液流变学各指标检测结果,并对血脂和血流变各项指标进行相关分析。[结果]脂肪肝组的甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-c)、血浆黏度、全血黏度(高、中、低切)、红细胞压积、卡松黏度高于对照组,而高密度脂蛋白胆固醇(HDL-c)、红细胞变形指数低于对照组,差异均具有统计学意义(P﹤0.05)。相关分析发现:脂肪肝组TC、TG与血浆黏度;TG与全血(高、中切)黏度、全血高切还原黏度、卡松黏度呈正相关;HDL-c与全血黏度(高、中、低切)、红细胞压积、全血高切还原黏度、卡松黏度呈负相关。[结论]脂肪肝患者表现为高TG为特点的血脂代谢紊乱和多项血液流变学指标的异常,部分血脂与血流变指标有密切关联。
[Objective] To investigate the characteristics of lipid and hemorheology in patients with fatty liver and their relationship. [Method] The results of blood lipids and hemorrheology in 310 patients with fatty liver and 246 normal controls were compared. The correlations between the indexes of blood lipid and blood rheology were analyzed. [Results] The triglyceride (TG), low density lipoprotein cholesterol (LDL-c), plasma viscosity, whole blood viscosity (high, middle and low cut), hematocrit and cardon viscosity of fatty liver group were higher than those of control HDL-c and erythrocyte deformability index were lower than the control group (P <0.05). Correlation analysis showed that there was a positive correlation between TC, TG and plasma viscosity in fatty liver group, TG, viscosity in whole blood (high and middle), reducing viscosity in whole blood, viscosity of card, HDL-c and whole blood viscosity , Low cut), hematocrit, reduction of whole blood high shear viscosity, viscosity of card is negatively correlated. [Conclusion] Patients with fatty liver show dyslipidemia and many abnormalities of hemorheology, which are characterized by high TG. Some lipids are closely related to indexes of hemorheology.