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本文对52例慢性肾功能不全不同临床分期即肾功能正常期、氮质血症期、尿毒症期患者及正常人血清中可溶性白细胞介素-2受体(sIL-2R)水平进行了检测,结果分别为213±46.5,33.3±81,8,568±198.7,197±44.2(u/ml)。表明慢性:肾功能不全肾功能正常期患者血清中sIL-2R与正常人血清中sIL-2R水平无明显差异;而氨质血症期与尿毒症期患者sIL-2R均明显高于正常人(P<0.01),且sIL-2R水平与血中尿素氮及肌酐含量呈一定的平行关系。提示sIL-2R测定,对慢性肾功能不全患者的病情监测、临床分期、药物治疗效果及预后判断等都有一定的参考价值。
In this paper, serum IL-2R levels were measured in 52 patients with different clinical stages of chronic renal insufficiency, ie, normal renal function, azotemia, uremia patients and normal persons, Results were 213 ± 46.5, 33.3 ± 81, 8,568 ± 198.7, 197 ± 44.2 (u / ml), respectively. Chronic: Renal insufficiency in patients with normal renal function in serum sIL-2R and normal serum sIL-2R levels no significant difference; while the serum levels of sIL-2R in patients with serum ammonia and uremia were significantly higher than normal ( P <0.01). The levels of sIL-2R and blood urea nitrogen and creatinine were in a parallel relationship. Tip sIL-2R determination of chronic renal insufficiency in patients with disease monitoring, clinical staging, drug treatment and prognosis have a certain reference value.