腹泻相关性溶血性尿毒综合征(HUS)是儿童急性肾衰的主要原因之一。研究表明,产志贺毒素的大肠埃希菌(E.coli)是大多数腹泻相关性HUS的病原因素。在美国,最常见的产志贺毒素的E.coli是E.coli O157:H7,估计感染总数为73480例,3％-15％的患者在腹泻发作后发生HUS。其危险因素包括:年幼或年老、白细胞数增多、使用抗微生物药或抗动力药,但有关临床特征知之甚少。纽约自1994年7 Diarrhea-associated hemolytic uremic syndrome (HUS) is one of the major causes of acute renal failure in children. Studies have shown that Shiga toxin-producing Escherichia coli is the causative agent of most diarrhea-related HUS. In the United States, the most common Shiga-producing E. coli is E. coli O157: H7, with an estimated total of 73,480 infections and 3% -15% of patients developing HUS following a diarrhea episode. The risk factors include: young or old, increased white blood cell count, the use of anti-microbial drugs or anti-drug, but little is known about the clinical features. New York since 1994 7