牙源性囊肿的恶变率为0.31％～2％,下颌约为上颌的4倍。本文报道2例恶变牙源性囊肿。 病例1,女,52岁,有癌家族史。左下前磨牙区肿痛2月。口内左下无牙,牙槽颊舌侧触痛及弥散肿胀,舌侧有一瘘道,颏神经和舌神经支配范围无异常改变。全景片示3.5cm×1.5cm椭圆形透光区,从左下尖牙延伸至左下第一磨牙,位于颏孔及下齿槽神经管之上。术中 Malignant rate of odontogenic cyst is 0.31% ~ 2%, jaw about 4 times the maxillary. This article reports 2 cases of malignant dendritic cysts. Case 1, female, 52 years old, have a family history of cancer. Lower left premolar area swelling and pain in February. There was no tooth loss in the lower left mouth, tenderness in the buccal and lingual alveoli, and swelling and swelling in the mouth. There was a fistula on the lingual side, and there was no abnormal change in the dominance of the chin nerves and lingual nerve. The panoramic film shows 3.5cm × 1.5cm oval light transmission area, extending from the left lower canine to the lower left first molars, located above the mental foramen and lower alveolar neural tube. Intraoperative