论文部分内容阅读
目的了解妇科疾病患者人乳头瘤病毒(HPV)感染情况及其影响因素,为临床防治提供参考依据。方法收集2010年1月—2015年10月在山东省医学科学院附属医院妇科门诊就诊的1 680例妇科疾病患者的病历资料。结果 1 680例妇科疾病患者中,HPV感染者590例,HPV感染率为35.12%。590例HPV感染妇科患者中,单一型感染453例(76.78%),双重感染95例(16.10%),多重感染42例(7.12%);低危型感染194例(32.88%),高危型感染396例(67.12%)。多因素非条件logistic回归分析结果显示,怀孕次数≥2次和性伴侣数量≥2个是妇科疾病患者HPV感染的危险因素,文化程度大专及以上、首次性生活年龄≥21岁和使用避孕套避孕是妇科疾病患者HPV感染的保护因素。结论妇科疾病患者HPV感染以单一型、高危型感染为主;文化程度、首次性生活年龄、怀孕次数、是否使用避孕套避孕和性伴侣数量是妇科疾病患者HPV感染的主要影响因素。
Objective To understand the human papillomavirus (HPV) infection and its influencing factors in patients with gynecological diseases and provide reference for clinical prevention and treatment. Methods A total of 1 680 cases of gynecological diseases were collected from gynecological clinic of Shandong Provincial Academy of Medical Sciences from January 2010 to October 2015. Results Among 1 680 cases of gynecological diseases, 590 were HPV-infected and the HPV infection rate was 35.12%. Among 590 cases of HPV infection, 453 cases (76.78%) were single type infection, 95 cases (16.10%) were double infection, 42 cases (7.12%) were multiple infection, 194 cases (32.88%) were low-risk infection, 396 cases (67.12%). Multivariate non-conditional logistic regression analysis showed that the number of pregnancies ≥ 2 times and the number of sexual partners ≥ 2 were risk factors for HPV infection in patients with gynecological diseases. The educational level of college and above, the first-time sexual life ≥21 years and the use of condom contraception Is a protective factor for HPV infection in patients with gynecological diseases. Conclusion The prevalence of HPV infection in gynecological diseases is mainly single type and high risk type. The level of education, the age of first sex, the number of pregnancies, whether or not condom is used and the number of sexual partners are the main influencing factors of HPV infection in patients with gynecological diseases.