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对老年人群冠心病(CHD)患病率和发病率及其相关危险因素进行分析研究。选择 1996年 5月～ 1997年 6月在本院接受健康查体 ,年龄 6 0岁以上的无CHD的老年人群作为基线人群 ,随访至 2 0 0 0年 6月。糖尿病 (DM)诊断分别按照 1985年WHO和 1997年美国糖尿病学会 (ADA)标准确定。计算基线时CHD患病率 ,采用人年法计算其发病率 ,同时还采用Logistic回归分析对 4年中新发的CHD危险因素进行分析。基线时按 1985年WHO标准 ,糖耐量低减组(IGT)和DM组的CHD和心肌梗死(MI)患病率均明显高于糖耐量正常组 (NGT) (P <0 0 5 ,P <0 0 1)。基线时无CHD人群 875例 ,老年人群CHD的发病率为 34 2 6 /10 0 0人年 ,其中IGT和DM组分别为5 0 4 2和 5 7 0 8/10 0 0人年 ,明显高于NGT组的 2 7 5 5 /10 0 0人年 (P <0 0 5 ,P <0 0 1)。Logistic逐步回归分析表明 ,DM、IGT、高血压(HT)、体重指数 (BMI)和年龄与CHD发生明显相关 ;按ADA诊断标准分类 ,与CHD发生密切相关的危险因素为年龄、HT和DM ,空腹血糖异常 (IFG)与CHD的发生无明显关系(P >0 0 5 )。老年人群中按 1985年WHO标准诊断的IGT和DM组的CHD患病率和发病率明显高于NGT组 ,糖代谢异常、高血压、肥胖和增龄与CHD发病密切相关。而按ADA诊断标准 ,只有糖尿病 (DM)的CHD患?
The prevalence and incidence of coronary heart disease (CHD) in elderly population and its related risk factors were analyzed. Choose the elderly without CHD over 60 years of age from May 1996 to June 1997 in our hospital as the baseline population and follow up to June 2000. Diabetes mellitus (DM) was diagnosed in accordance with the 1985 WHO and 1997 American Diabetes Association (ADA) standards. The prevalence of CHD at baseline was calculated and the incidence of CHD was calculated using the human age method. Risk factors for new-onset CHD in 4 years were also analyzed using Logistic regression analysis. At baseline, prevalence of CHD and MI in IGT and DM groups was significantly higher than that in normal glucose tolerance group (NGT) according to WHO 1985 standard (P <0.05, P < 0 0 1). At baseline, there were 875 CHD-free and CHD incidences in the elderly population of 34 2 6/10 000 person-years, of which the IGT and DM groups were 542 and 5700/1000 person-years, respectively, significantly higher In the NGT group, there were 27 55/100 person-years (P <0.05, P <0.01). Logistic stepwise regression analysis showed that DM, IGT, high blood pressure (HT), body mass index (BMI) and age were significantly associated with CHD. According to ADA diagnostic criteria, the risk factors closely related to CHD were age, HT and DM, There was no significant relationship between fasting blood glucose (IFG) and the occurrence of CHD (P> 0.05). The prevalence and incidence of CHD in IGT and DM patients diagnosed by the 1985 WHO standard in the elderly population were significantly higher than those in the NGT group. The abnormal glucose metabolism, hypertension, obesity and aging were closely related to the incidence of CHD. According to ADA diagnostic criteria, only diabetes (DM) in patients with CHD?