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本文通过对近年发表的大量文献资料的综合、分析、研究,阐述降压药研究进展和今后发展方向:中枢降压药研究方向是寻找选择性突触后的α受体激动剂;β-阻滞剂的研究方向是寻找心脏选择性的高效长效β-阻滞剂;α-受体阻滞剂哌唑嗪衍生物颇有发展前途;血管紧张素转化酶抑制剂是相当成功的降压药;钙拮抗剂用作降压药不影响心脏或静脉回流,也不造成重要器官组织灌注不足的现象,因此比β-肾上腺素受体阻滞剂和其它降压药更有发展前途。
This article through a large number of literature published in recent years, synthesis, analysis, research, elaboration of antihypertensive drug research progress and future development: central antihypertensive drug research is looking for selective postsynaptic α receptor agonist; β-block The research direction of defibrillators is to find the cardiac selective and efficient long-acting β-blockers; prazosin derivatives of α-receptor blockers have a promising future; angiotensin converting enzyme inhibitors are quite successful in lowering blood pressure Drug; calcium antagonists as antihypertensive drugs do not affect the heart or venous return, and does not cause the phenomenon of insufficient perfusion of vital organs and therefore more promising than β-adrenergic receptor blockers and other antihypertensive drugs.