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目的 探讨前颅底肿瘤手术及术后颅底组织缺损修复方法。方法 对 1992～ 1999年间我院收治的 35例患者的手术方法、手术效果、并发症、生存率、修复材料和方法等进行回顾性分析。结果 本组并发症的发生率为 14.2 9% (5 /35例 ) ,35例中良性肿瘤共 11例 ,1例死于术后脑水肿伴全身衰竭 ,余 10例随访 7年皆健在。2 4例恶性肿瘤患者的 3年和5年生存率 (按生命表法计算 )分别为 5 8.0 7%和 36 .2 9%。结论 采用颅内外联合径路手术治疗前颅底区肿瘤是行之有效的方法之一。
Objective To explore the methods of anterior skull base tumor surgery and postoperative skull base defect repair. Methods Surgical methods, operative effects, complications, survival rates, repair materials and methods of 35 patients admitted to our hospital from 1992 to 1999 were analyzed retrospectively. Results The incidence of complications in this group was 14.2% (5/35). There were 11 cases of benign tumors in 35 cases, 1 case died of postoperative cerebral edema with systemic failure, and the remaining 10 cases were followed up for 7 years. The 3-year and 5-year survival rates (calculated by the life table method) of 24 patients with malignant tumors were 5 8.07% and 36.29%, respectively. Conclusion The treatment of anterior skull base tumor by intracranial and extracranial approach is one of the effective methods.