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轻度缺碘时缺硒或补硒可明显降低或增加大鼠组织硒含量和谷胱甘肽过氧化物酶（ＧＰｘ）活力，但随时间的延长各组织变化趋势不同。在４周内肝脏和肾硒含量和ＧＰｘ活力变化幅度大，在８周时红细胞的硒含量和ＧＰｘ活力仍有继续增加或降低的趋势。大脑和甲状腺硒含量和ＧＰｘ活力缺硒后反而升高，但增加幅度明显低于补硒后的增加幅度。提示大脑可优先得到硒，大脑和甲状腺具有较强的维持抗氧化状态的能力。肝脏、肾脏和红细胞可能分别是硒缺乏早期和后期重要器官硒的主要来源。红细胞可能起“硒储备库”的作用。
Lack of selenium or selenium in mild iodine deficiency can significantly reduce or increase selenium content and glutathione peroxidase (GPx) activity in rats, but with the extension of time trends in different organizations. Within 4 weeks, selenium content and GPx activity in the liver and kidney varied greatly. At 8 weeks, the selenium content and GPx activity of erythrocytes continued to increase or decrease. Selenium content and GPx activity of the brain and thyroid selenium but increased selenium, but the increase was significantly lower than the selenium after the increase. Tip brain priority selenium, the brain and thyroid have a strong ability to maintain the antioxidant status. Liver, kidney and red blood cells may be the main sources of selenium deficiency, selenium, an important organ of the early and late stages, respectively. Red blood cells may play a “selenium reserve bank” role.