论文部分内容阅读
目的：探讨肺鳞癌间质内微血管与肺癌临床病理的关系；方法：应用ＦⅧ相关抗体，并采用ＬＳＡＢ法对８９例手术切除的肺鳞癌微血管进行定量检测；结果：有淋巴结转移组肺鳞癌微血管密度每２００倍视野５０．２±２２．８个，无转移组为３４±１９．１个；有淋巴结转移组微血管腔面积为６９６１．８±２８６８．９平方象素，无转移组为４０３７．４±２４２５．３平方象素，两者在两组间比较，差异均有极显著性意义（ｔ＝３．１７，ｔ＝３．５８，Ｐ均＜０．０１）；微血管密度及腔面积在３组不同生存期的患者间差异亦均具有极显著性意义（Ｆ＝６．６２，Ｆ＝８．６５，Ｐ均＜０．０１）；结论：肺鳞癌间质内微血管生成与淋巴结转移和患者的预后有关。
OBJECTIVE: To investigate the relationship between intratumoral microvessels of lung squamous cell carcinoma and clinicopathology of lung cancer. Methods: FVIII-related antibody was applied to quantify microvessels of 89 cases of lung squamous cell carcinoma by LSAB method. Results: There were lymph nodes metastasis group lung scales. The tumor microvessel density was 50.2±22.8 per 200-fold visual field, and the non-metastasis group was 34±19.1; the lymphatic metastasis group had a microvascular lumen area of 6961.8±2868.9 square pixels, and the non-metastasis group was 4037.4±2425.3 square pixels, there was a significant difference between the two groups (t=3.17, t=3.58, P<0.01); microvessel density and The luminal area was also significantly different among the three groups of patients with different survival periods (F=6.62, F=8.65, P<0.01); Conclusion: Interstitial microvascular production in lung squamous cell carcinoma It is associated with lymph node metastasis and the patient’s prognosis.