神经肽广泛存在于交感神经系统中 ,在脊髓的中间侧柱、交感神经节和神经效应器接头等不同水平调节神经元信息传递活动。几种从下丘脑和延髓发出的含神经肽神经通路调节着节前神经元的兴奋性。在一些特定编码支配特定靶器官的交感神经节神经元群中 ,神经肽与去甲肾上腺素或乙酰胆碱共存。在发生过程中 ,神经肽的表达是可塑的 ,多种来源的神经肽调节交感神经节的突触传递。 Neuropeptides are widely found in the sympathetic nervous system and mediate neuronal signaling activities at various levels, such as the medial columella, sympathetic ganglia, and neuroendocrine junctions. Several neuropeptide-containing neuronal pathways emanating from the hypothalamus and medulla regulate the excitability of preganglionic neurons. Neuropeptides coexist with norepinephrine or acetylcholine in some groups of sympathetic ganglion neurons that specifically encode a particular target organ. During the course of neuropeptide expression is plastic, a variety of sources of neuropeptides regulate sympathetic ganglion synaptic transmission.