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目的:观察芪益强肾饮(自拟方)对慢性肾小球肾炎患者的蛋白尿、血尿及全身浮肿的改善和治疗作用,探讨其作用机制。方法:130例慢性肾小球肾炎患者随机分为两组,治疗组采用芪益强肾饮,对照组给予雷公藤多苷片,观察两组患者治疗前后24 h尿蛋白定量、尿常规(红细胞计数)变化情况。结果:治疗组总有效率84.1%,对照组71.9%,差异有统计学意义(P<0.05)。治疗组在改善症状,降低24 h尿蛋白定量、减少血尿方面疗效明显优于对照组(P<0.05)。结论:芪益强肾饮可显著缓解临床症状,降低尿蛋白、减少血尿,改善肾脏微循环,防止肾小球硬化,对慢性肾炎有良好的疗效。
Objective: To observe the Qiliqiangshenyin (self-prescription) on patients with chronic glomerulonephritis proteinuria, hematuria and systemic edema to improve and treat the role of mechanism. Methods: 130 patients with chronic glomerulonephritis were randomly divided into two groups. The treatment group was treated with Qiyqiangshenyin, and the control group was given Tripterygium Wilfordii glycosides tablets. Urinary protein, urine routine (RBC Count) changes. Results: The total effective rate was 84.1% in the treatment group and 71.9% in the control group, the difference was statistically significant (P <0.05). The treatment group was significantly better than the control group (P <0.05) in improving symptoms, reducing 24 h urine protein and reducing hematuria. Conclusion: Qiyqiangshen drink can significantly relieve clinical symptoms, reduce urinary protein, reduce hematuria, improve renal microcirculation, prevent glomerulosclerosis, have a good effect on chronic nephritis.