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目的评价原发性肝癌根治性切除术后肝动脉灌注化疗与门静脉灌注化疗的疗效，探讨原发性肝癌根治性切除术后复发及转移的预防途径。方法经病理确诊的原发性肝癌７５例，其中４２例行根治性切除及术后选择性肝动脉插管化疗，３３例行根治性切除及术后门静脉灌注化疗。每隔１～３个月重复，定期复查。结果原发性肝癌切除术后肝动脉灌注化疗组的术后复发率（２１．４３％）低于门静脉灌注化疗组（３６．３６％），且生存时间（１１．４个月）明显较门静脉灌注化疗组（７．６个月）长，而门静脉灌注化疗组的转移率（９．０９％）明显低于肝动脉灌注化疗组（３２．１４％）。结论原发性肝癌根治性切除术后行肝动脉灌注化疗较门静脉灌注化疗疗效好，而原发性肝癌切除术后同时结合肝动脉、门静脉灌注化疗对术后预防肿瘤的复发与转移可能更为理想
Objective To evaluate the efficacy of hepatic arterial infusion chemotherapy and portal vein infusion chemotherapy after radical resection of primary liver cancer, and to explore the preventive approaches for the recurrence and metastasis of primary liver cancer after radical resection. Methods A total of 75 patients with pathologically confirmed primary liver cancer were included. Among them, 42 patients underwent radical resection and selective hepatic artery catheterization chemotherapy. 33 patients underwent radical resection and postoperative portal vein chemotherapy. Repeat every 1 to 3 months and review regularly. Results The postoperative recurrence rate of hepatic artery infusion chemotherapy group (21.43%) was lower than that of portal vein chemotherapy group (36.36%), and the survival time (11.4 months) was significantly higher than that of portal vein. Infusion chemotherapy group (7.6 months) long, and portal vein infusion chemotherapy group metastasis rate (9.09%) was significantly lower than hepatic artery infusion chemotherapy group (32.14%). Conclusion The curative effect of hepatic artery infusion chemotherapy after radical resection of primary liver cancer is better than that of portal vein infusion chemotherapy. The combination of hepatic artery and portal vein infusion chemotherapy after primary hepatic carcinoma resection may be more effective in preventing tumor recurrence and metastasis after primary hepatic carcinoma. ideal