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在本研究中,我们选择了90例外科腹腔内感染病人,随机分为二组,一组为厌氧灵治疗组,一组为氨苄十灭滴灵治疗组。所有病例于术中取材,进行细菌学调查。二组病人分别于术前一日用药至术后四日,观察体温、白细胞变化,排气时间,切口感染率。结果表明,本组病例中,厌氧菌的检出率为56.7%,需氧菌的检出率为54.4%。术后第三日,二组病例的体温恢复正常;白细胞计数氨苄十灭滴灵组(10.14±2.84×109/L)较厌氧灵组(8.94±2.31×109/L)轻度升高,(P<0.05);厌氧灵组的排气时间(2.31±0.53天),早于氨苄十灭滴灵组(3.07±0.52天)(P<0.01);厌氧灵组的切口感染率虽低于氨苄十灭滴灵组,但无统计学意义。提示厌氧灵在临床应用中对防治腹内感染有较好的效果。
In this study, we selected 90 patients with surgical intraperitoneal infection, were randomly divided into two groups, one for the anorexia treatment group, one for the ampicillin metronidazole treatment group. All cases were drawn intraoperatively for bacteriological investigation. Two groups of patients were treated on the first day before surgery to four days after surgery to observe the body temperature, leukocyte changes, exhaust time, incision infection rate. The results showed that in this group of cases, the detection rate of anaerobic bacteria was 56.7% and the detection rate of aerobic bacteria was 54.4%. On the third postoperative day, the body temperature in the two groups returned to normal; the white blood cell count was significantly lower in the aninaloxazine group (10.14 ± 2.84 × 109 / L) than in the analectin group (8.94 ± 2.31 × 109 / L) (P <0.05). The exhaust time of anorexia group (2.31 ± 0.53 days) was earlier than that of the vehicle group (3.07 ± 0. 52 days) (P <0.01). The infection rate of anaerobic group was lower than that of metronidazole and metronidazole group, but it was not statistically significant. Tip anaerobic in the clinical application of intra-abdominal infection prevention and treatment has a good effect.