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据对苯丙咪唑氨基甲酸酯类化合物对寄生线虫作用方式的生物化学研究,认为其作用部位是虫的微管。甲苯咪唑对盘尾丝虫的暂时性胚胎毒作用提示可能该虫的胚胎微管对甲苯咪唑有选择的敏感性。研究能抑制微管合成或聚合的新化合物有赖于复杂的生物
According to biochemical studies on the mode of action of benzimidazole carbamates on parasitic nematodes, it is believed that the site of action is the microtubules of the worms. Temporal embryotoxic effects of mebendazole on onchocerciasis suggest that the embryo microtubules of this insect may be selectively sensitized to mebendazole. Research on new compounds that inhibit microtubule synthesis or polymerization depends on complex organisms