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目的探讨低浓度苯接触工人的健康状况及影响因素。方法对823名研究对象(直接接苯组253人,间接接苯组482人,对照组88人)进行健康体检,采用χ2检验比较各组卫生习惯、临床症状及白细胞降低率差异,采用logistic回归分析白细胞降低的影响因素。结果直接接苯组经常使用防护用品人数的比例(78.3%)明显高于间接接苯组(55.2%)(P<0.05);间接接苯组和直接接苯组白细胞波动率(32.2%,40.7%)及白细胞降低率(20.5%,27.7%)均高于对照组(6.8%,0),差异有统计学意义(P<0.05);苯暴露、年龄和接苯工龄是白细胞降低的影响因素。结论低浓度苯接触仍可能会产生血液毒性,白细胞计数是监测低浓度苯接触血液毒性的一个敏感指标。
Objective To investigate the health status and influential factors of low-concentration benzene exposure workers. Methods A total of 823 subjects (253 directly exposed to benzene, 482 indirectly exposed to benzene, and 88 controls) were tested for physical examination. Chi-square test was used to compare the differences in hygiene habits, clinical symptoms and leukopenia. Logistic regression Analysis of the influencing factors of leukopenia. Results The proportion of patients with direct use of protective equipment (78.3%) receiving benzene directly was significantly higher than that of indirectly receiving benzene (55.2%) (P <0.05). The leukocyte volatility (32.2%, 40.7% %) And leukopenia (20.5%, 27.7%) were higher than the control group (6.8%, 0), the difference was statistically significant (P <0.05); benzene exposure, age, . Conclusions Exposure to benzene at low concentrations may still produce hematotoxicity and leukocyte count is a sensitive indicator of blood toxicity in low-concentration benzene exposure.