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目的分析浙江省2005—2014年钩端螺旋体病(钩体病)监测资料,探索浙江省钩体病流行规律。方法采用描述性流行病学方法分析人间钩体病疫情数据;采集鼠肾、蛙肾、猪肾、牛尿、鸭肾、鸭血和蛙血进行病原体分离培养,临床确诊病例和宿主动物采用显微镜凝集实验检测抗体,分析宿主动物和人群中钩端螺旋体流行菌群携带和变动情况。结果浙江省2005—2014年累计发病131例,死亡3例,报告发病率为0.025 2/10万,死亡率为0.000 6/10万,病死率为2.29%。2007年发病率最高,为0.108 4/10万。除舟山市和湖州市外,其余各市均有病例报告,病例主要集中在浙中和浙南山区。40~65岁人群是钩体病的高发人群,占75.57%。宿主动物以携带黄疸出血群为主,占68.50%;鸭血阳性率最高,为23.94%。人群血清抗体种群以秋季群和黄疸出血群为主。结论 2005—2014浙江省钩体病疫情维持在较低水平,宿主动物携带菌群相对稳定。
Objective To analyze the surveillance data of leptospirosis (leptospirosis) from 2005 to 2014 in Zhejiang Province and explore the prevalence of leptospirosis in Zhejiang Province. Methods Descriptive epidemiological method was used to analyze the data of LES. The pathogen was isolated and cultured from rat kidney, frog kidney, pig kidney, cow urine, duck kidney, duck blood and frog blood. The clinically confirmed cases and host animals were examined by microscope Agglutination test antibody detection, analysis of host animals and populations of Leptospira epidemic flora and changes. Results A total of 131 cases and 3 deaths were reported from 2005 to 2014 in Zhejiang Province. The reported incidence rate was 0.025 2 / 100,000 with a mortality rate of 0.0006 / 100,000 and a case fatality rate of 2.29%. The highest incidence in 2007 was 0.108 4/10 million. In addition to Zhoushan City and Huzhou City, the rest of the cities have reported cases, the cases are mainly concentrated in the Zhejiang and Zhejiang mountainous areas. 40 to 65-year-old population is a high prevalence of leptospirosis, accounting for 75.57%. Host animals to carry jaundice bleeding group, accounting for 68.50%; duck blood positive rate was 23.94%. The population of serum antibody population is dominated by autumn group and jaundice bleeding group. Conclusion The epidemic situation of leptospirosis in Zhejiang Province was maintained at a low level from 2005 to 2014, and the flora of host animals was relatively stable.