苦豆子系豆科植物Sophora alopecuroioles L,本文观察到苦豆子总碱在约1/5LD_(50)剂量作用下,能抑制小鼠的自主活动加强戊巴比妥钠和氯丙嗪对中枢神比系统的抑制作用,拮抗咖啡因的中枢兴奋作用。小鼠扭体法和烫尾法显示有镇痛效应。正常大鼠应用本品后,可出现降温现象。表明总碱具有镇静、镇痛、降温等中枢抑制效应,本品对戊四氮和士的宁惊厥无对抗作用,反可 Sophora alopecuroiole L is a leguminous plant. It was observed that the total alkaloids of Sophora flavescens inhibited the autonomous activity of mice by about 1/5 LD_(50) dose and enhanced the concentration of pentobarbital sodium and chlorpromazine on the central nervous system. The inhibitory effect of the system antagonizes the central stimulant effect of caffeine. The mouse writhing method and the hot tail method showed analgesic effect. After normal use of this product, there may be cooling phenomenon. Shows that total alkaloids have central inhibitory effects such as sedation, analgesia, and cooling. This product has no antagonistic effect on Pentylenetetrazol and strychnine, but can