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用细胞培养法、PCR和IFA检测145例不育症育龄妇女及45例正常育龄妇女宫颈拭子沙眼衣原体(CT)及解脲脲原体(Uu),并以强力霉素和四环素治疗阳性病例。结果示,用细胞培养,PCR,培养片IFA及直接涂片IFA检测不育症组宫颈CT,检出率分别为62.7%,66.8%,64.8%和36.5%,明显高于对照组(P<0.01);Uu分离率为33.1%;CT与Uu合并感染率为18.6%,两者均明显高于对照组(P<0.01)。表明宫颈CT和Uu感染是引起女性不育的重要因素。强力霉素、四环素治疗效果并不理想
145 cases of infertility women of childbearing age and 45 normal women of childbearing age were enrolled in this study. CT and Uu were detected by cell culture, PCR and IFA. Positive cases were treated with doxycycline and tetracycline . The results showed that the detection rate of cervical CT in infertility group was 62.7%, 66.8%, 64.8% and 36.5% respectively by cell culture, PCR, IFA and IFA, (P <0.01). The Uu isolation rate was 33.1%. The combined infection rate of CT and Uu was 18.6%, both of which were significantly higher than that of the control group (P <0.01). Cervical and Uu cervical infection that is an important factor in female infertility. Doxycycline, tetracycline treatment is not ideal