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目的:对抗感染药物的不良反应进行了解和分析,为抗感染药物的临床合理用药提供依据。方法:对本院2010年3月-2011年3月抗感染药物的不良反应报告进行收集,分别分析总结患者状况、给药途径、抗感染药物类别、抗感染情况以及不良反应临床表现。结果:30例抗感染药物的不良反应中,喹诺酮类药物不良反应例数最多,9例,占30.00%,其次为头孢菌素类5例,16.67%。。不良反应发生器官主要是皮肤及其附件,其次是消化系统。结论:抗感染药物的临床不合理用药是药物不良反应发生的主要原因之一,应该在临床上予以重视和监管。
OBJECTIVE: To understand and analyze the adverse reactions of the infected drugs and provide evidences for the clinical rational use of anti-infective drugs. Methods: The adverse reactions of anti-infectives from March 2010 to March 2011 in our hospital were collected. The status of patients, route of administration, categories of anti-infectives, anti-infectives and the clinical manifestations of adverse reactions were analyzed. Results: Among the 30 adverse reactions of anti-infectives, quinolone had the most adverse reactions in 9 cases (30.00%), followed by 5 cases of cephalosporins (16.67%). . Adverse reactions occur mainly in the skin and its appendages organs, followed by the digestive system. Conclusion: The clinical irrational use of anti-infective drugs is one of the major causes of adverse drug reactions and should be taken seriously and supervised in clinical practice.