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目的:探讨血清C反应蛋白(CRP)及红细胞压积(HCT)在重症急性胰腺炎诊断中的应用价值。方法:纳入70例急性胰腺炎患者为病例组,其中轻型胰腺炎(MAP)组40例,重症胰腺炎(SAP)组30例。选择同期住院非感染、肝脏、胆道、胰腺疾病30例患者为对照组。测定各组患者入院24 h内血清HCT及CRP水平,比较其在不同分组间的差异及通过ROC曲线了解其在重症胰腺炎诊段中的价值。结果:MAP组、SAP组患者血清HCT、CRP水平明显高于对照组(P<0.05)。SAP组患者血清HCT、CRP水平明显高于MAP组(P<0.05)。ROC曲线显示入院血清HCT及CRP水平诊断重症胰腺炎曲线下面积(AUC)分别为0.783、0.828。结论:血清HCT及CRP水平可有效评估急性胰腺炎患者病情的严重程度,其可作为诊断重症胰腺炎的早期指标。
Objective: To investigate the value of serum C-reactive protein (CRP) and hematocrit (HCT) in the diagnosis of severe acute pancreatitis. Methods: Seventy patients with acute pancreatitis were enrolled in the study. Forty patients with mild pancreatitis (MAP) and 40 with severe pancreatitis (SAP) were enrolled. Select the same period of hospital non-infection, liver, biliary, pancreatic disease in 30 patients as control group. The levels of serum HCT and CRP within 24 hours after admission were determined, and their differences in different groups were compared. The value of ROC curve in diagnosis of severe pancreatitis was also obtained. Results: The levels of serum HCT and CRP in MAP group and SAP group were significantly higher than those in control group (P <0.05). The levels of serum HCT and CRP in SAP group were significantly higher than those in MAP group (P <0.05). The ROC curve showed that the area under the curve (AUC) of serum HCT and CRP levels in diagnosis of severe pancreatitis were 0.783,0.828. Conclusion: Serum HCT and CRP level can effectively assess the severity of the disease in patients with acute pancreatitis, which can be used as an early indicator of the diagnosis of severe pancreatitis.