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为了评价减量静脉给药或雾化吸入戊烷脒治疗轻至中度卡氏肺孢子虫性肺炎的疗效及其毒性作用,将轻至中度(PaO_2≥7.3kPa[55mmHg])第一次发作卡氏肺孢子虫性肺炎的45名艾滋病患者随机分为两组。其中22例接受戊烷脒静脉给药治疗,剂量为3mg/kg·d,23例接受戊烷脒雾化治疗,剂量为600mg。两种方法均为每日1次,持续2～3wk。结果显示:静脉给药组22个病人中有1人无评价价值,雾化组23个病人中有6人无
In order to evaluate the efficacy and toxicity of intravenous or nebulized pentamidine in patients with mild to moderate pneumocystis carinii pneumonia, mild to moderate (PaO 2 ≥7.3 kPa [55 mmHg]) Forty-five AIDS patients with episodes of pneumocystis carinii pneumonia were randomly assigned to two groups. Twenty-two of these patients received pentamidine intravenously, at a dose of 3 mg / kg · d, and 23 received pentamidine nebulization at a dose of 600 mg. Both methods are daily 1, lasting 2 ~ 3wk. The results showed that: one of 22 patients in the intravenous group had no evaluation value, and 6 of 23 patients in the nebulized group had no