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目的:分析讨论非甾体抗炎药相关性消化性溃疡的临床特征。方法:选取我院2013年1月-2014年6月间52例消化性溃疡的患者,其中A组26例为相关性消化性溃疡,B组26例为非相关性消化性溃疡,对两种消化性溃疡的临床特征进行比较。结果:A组患者胃溃疡7例,十二指肠溃疡6例,复合型溃疡13例,溃疡为单发性的9例,多发性的17例,有15例患者合并糜烂症状。B组患者胃溃疡13例,十二指肠溃疡11例,复合型溃疡2例,其中单发性溃疡19例,多发性溃疡7例,5例患者合并出现糜烂症状,A组出现黑便的患者21例,呕血患者16例,消化不良患者2例。B组出现黑便的患者为3例,呕血的患者4例,消化不良的患者17例。两组比较,差异有统计学意义(P<0.05或P<0.01)。结论:非甾体抗炎药相关性消化溃疡多以复合型溃疡出现,且多发于有慢病史的患者中。
Objective: To analyze and discuss the clinical features of peptic ulcer associated with NSAIDs. Methods: Fifty-two patients with peptic ulcer were selected from January 2013 to June 2014 in our hospital. Among them, 26 cases in group A were related peptic ulcer, 26 cases in group B were unrelated peptic ulcer, The clinical features of peptic ulcer were compared. Results: A group of patients with gastric ulcer in 7 cases, duodenal ulcer in 6 cases, complex ulcer in 13 cases, ulcer in 9 cases of solitary, multiple in 17 cases, 15 patients with erosion symptoms. B group of patients with gastric ulcer in 13 cases, 11 cases of duodenal ulcer, 2 cases of complex ulcers, including 19 cases of single ulcer, multiple ulcers in 7 cases, 5 patients combined erosion symptoms, A group appeared melena 21 patients, hematemesis in 16 patients, 2 patients with dyspepsia. There were 3 patients with melena in group B, 4 patients with hematemesis, and 17 patients with dyspepsia. The difference between the two groups was statistically significant (P <0.05 or P <0.01). Conclusion: Non-steroidal anti-inflammatory drug-related peptic ulcer mostly occurs with compound ulcer and is frequently found in patients with a history of chronic disease.