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兴奋剂成瘾者有渐增趋势,因其合并血管炎而引起颅内出血的病例正在增加。作者报告1例女患,22岁,连续数年使用兴奋剂,一年前停药。发病前静注MAP(量不详),数分钟后全身痉挛、昏睡。Bp160/100mmHg,P81次/分,呼吸不整,血中查出MAP37.4μg/100g。颅平片正常。CT示明显蛛网膜下腔出血和胼胝体膝干部血肿。脑血管造影,两侧C_1部呈非灌注形,右胼胝体周围动脉可见造影剂外溢。尸解:肉眼见小脑扁桃体及钩回疝,脑表及脑基底部可见明显蛛网膜下腔出血,胼胝体膝、脑干内可见鸡卵大的血肿。切面示中度脑室内血肿。组织学检查发现脑血管中膜平滑
Stimulant addicts are on the rise, as cases of intracranial hemorrhage due to vasculitis are on the rise. The authors report a female patient, aged 22, who used doping for several years in a row and discontinued a year ago. Before the onset of intravenous MAP (an unknown amount), a few minutes after the body spasms, lethargy. Bp160 / 100mmHg, P81 times / min, respiratory insufficiency, found in the blood MAP37.4μg / 100g. Plain skull normal. CT showed subarachnoid hemorrhage and corpus callosum knee hematoma. Cerebral angiography, both sides of C_1 was non-perfusion, right corpus callosum visible peripheral contrast agent spilled. Autopsy: the naked eye see the cerebellum tonsils and hook hernia, brain and basal ganglia showed obvious subarachnoid hemorrhage, corpus callosum, knee, hematoma can be seen in the brainstem. Section showed moderate intraventricular hematoma. Histological examination revealed that the cerebrovascular membrane was smooth