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目的探讨双水平气道正压通气联合噻托溴铵吸入对老年慢性阻塞性肺疾病稳定期患者的临床疗效。方法 80例老年慢性阻塞性肺疾病稳定期患者,随机分为观察组和对照组,每组40例。对照组行双水平气道正压通气治疗,观察组在此基础上联合噻托溴铵吸入治疗,比较两组别患者的临床疗效。结果观察组患者的治疗总有效率明显优于对照组(P<0.05);两组患者治疗前肺功能指标比较,差异无统计学意义(P>0.05),治疗后两组患者均有所改善,但观察组明显优于对照组(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论双水平气道正压通气联合噻托溴铵吸入在老年慢性阻塞性肺疾病稳定期患者的治疗中可发挥良好的效果,可改善患者肺功能,提高治疗效果,且不良反应少,应推广应用。
Objective To investigate the clinical effect of dual-level positive airway pressure ventilation combined with tiotropium inhalation on elderly patients with chronic obstructive pulmonary disease (COPD) at stable stage. Methods Eighty elderly patients with chronic obstructive pulmonary disease were randomly divided into observation group and control group, 40 cases in each group. The control group received double-level positive airway pressure ventilation. The observation group was treated with tiotropium inhalation on this basis, and the clinical efficacy was compared between the two groups. Results The total effective rate of observation group was significantly better than that of control group (P <0.05). There was no significant difference in the index of pulmonary function between the two groups before treatment (P> 0.05), and both groups improved after treatment , But the observation group was significantly better than the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusions Biphasic positive airway pressure ventilation combined with tiotropium inhalation can play a good role in the treatment of elderly patients with chronic obstructive pulmonary disease (COPD) at stable stage, which can improve pulmonary function and improve the therapeutic effect with less adverse reactions and should be promoted application.