论文部分内容阅读
博莱霉素(Bleomycin,简称BLM)是多肽素抗肿瘤药物,单次气管内注射BLM可复制出与人肺间质性疾病相似的动物模型,但发病机理迄今未明。我们观察了腹腔内注射丹参酮ⅡA磺酸钠对BLM所致的SD大白鼠急性肺损伤的保护作用。
Bleomycin (abbreviated as BLM) is an anti-cancer drug for polypeptides. A single intratracheal injection of BLM can replicate an animal model similar to human pulmonary interstitial disease, but the pathogenesis is still unknown. We observed the protective effect of intraperitoneal injection of sodium tanshinone IIA sulfonate on BLM-induced acute lung injury in SD rats.