建立了毛细管电泳同时分析１１种常见还原单糖的２－氨基吖啶酮胺化还原衍生物的方法。衍生反应在４５°Ｃ进行５ｈ，用毛细管电泳分离，于波长２６４ｎｍ在线检测单糖衍生物。单糖的化学衍生极限为１０μｍｏｌ／Ｌ，单糖的浓度和质量检测极限分别为０．６μｍｏｌ／Ｌ和１７ｆｍｏｌ。在实验浓度５～２５μｍｏｌ／Ｌ范围内，这１１种单糖衍生物的峰积分面积与保留时间的比值关于单糖浓度的线性相关系数均在０．９９２（ｎ＝６）以上。对糖结构影响衍生物电迁移率的内在因素作了讨论。同时应用建立的方法分析了数个糖蛋白Ｎ－糖链组成成分。 A method for simultaneous determination of 2-aminoacridone aminated derivatives of 11 kinds of common monosaccharides by capillary electrophoresis was established. The derivatization reaction was carried out at 45 ° C for 5 h, separated by capillary electrophoresis and the monosaccharide derivative was detected online at a wavelength of 264 nm. The chemical derivatization limit of monosaccharides was 10μmol / L, the monosaccharide concentration and quality detection limit were 0.6μmol / L and 17fmol, respectively. In the range of 5 ~ 25μmol / L, the linear correlation coefficients of peak integral area and retention time of the 11 kinds of monosaccharide derivatives with respect to monosaccharide concentration were both above 0.992 (n = 6). The intrinsic factors that affect the electromigration mobility of the derivatives are discussed. At the same time, the method of establishing the method was used to analyze the composition of several glycoproteins.