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目的:了解胃肠术后中心静脉导管相关性血栓的发生率，探讨其形成的危险因素。方法:前瞻性分析衡水市哈励逊国际和平医院胃肠外科2018年5月至2019年5月行手术治疗并置入中心静脉导管的患者124例，收集可能与导管相关性血栓形成有关的影响因素，拔除中心静脉导管前常规行超声筛查，根据是否形成血栓分为血栓组(n n＝66)和非血栓组(n n＝58)，将两组间差异有统计学意义的影响因素进行多因素logistic回归。n 结果:经超声检查共有66例患者诊断为导管相关性血栓，发生率为53.2%(66/124)，其中63例无临床症状(50.8%)，仅有3例出现了临床症状，有症状的导管相关性血栓发生率为2.4%(3/124)。两组间手术类型、中心静脉导管留置时间、术后第3天纤维蛋白原及术后第3天D-二聚体差异均有统计学意义(χn 2＝21.415、7.651，n t＝5.7181、0.418，均n P<0.05)，进一步行多因素logistic回归提示手术类型(n OR＝0.157，95%n CI：0.040～0.612，n P＝0.008)、术后第3天纤维蛋白原(n OR＝7.371，95%n CI：2.318～23.442，n P＝0.001)、术后第3天D-二聚体(n OR＝6.920，95%n CI：2.854～16.783，n P＝0.000)是胃肠外科术后导管相关血栓的独立危险因素。n 结论:胃肠道术后中心静脉导管相关性血栓的发生率较高，多数患者无明显临床症状。肿瘤手术、术后第3天纤维蛋白原及术后第3天D-二聚体异常升高的患者要警惕导管相关性血栓的发生。“,”Objective:To investigate the incidence and risk factors of central venous catheter-related thrombosis after gastrointestinal surgery.Methods:From May 2018 to May 2019, 124 patients who received surgical treatment with central venous catheter placement in gastrointestinal surgery department at Harrsion International Peace Hospital were prospectively analyzed, and the factors that may be related to catheter-related thrombosis were collected.And performed ultrasound screening before the removal of central venous catheter, According to whether there was thrombosis or not, they were divided into thrombosis group(n n=66) and non-thrombosis group(n n=58). Multivariate logistic regression analysis was performed for the factors with statistical differences between the two groups.n Results:A total of 66 patients were diagnosed with catheter-related thrombus by ultrasonography, with an incidence of 53.2%(66/124), 63 cases with no clinical symptoms(50.8%), only 3 cases with clinical symptoms, and the incidence of catheter-related thrombus with symptoms was 2.4%(3/124). The operation type, central venous catheter indwelling time, fibrinogen on the 3rd day after surgery and D-dimer on the 3rd day after surgery between the two groups had statistically significant differences (χn 2=21.415, 7.651, n t=5.7181, 0.418, all n P<0.05). Multivariable logistic regression analysis showed that operation type(n OR=0.157, 95%n CI: 0.040-0.612, n P=0.008), fibrinogen on the 3rd day after surgery(n OR=7.371, 95%n CI: 2.318-23.442, n P=0.001), D-dimer on the 3rd day after surgery(n OR=6.920, 95%n CI: 2.854-16.783, n P=0.000) were independent risk factors of catheter-related thrombosis.n Conclusion:The incidence of central venous catheter-related thrombosis is higher after gastrointestinal surgery, and most patients have no obvious clinical symptoms.The patients who undergoing tumor surgery or with abnormal levels of fibrinogen and D-dimer on the 3rd day after surgery should aware of catheter-related thrombosis.