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目的:探讨在宫颈上皮内瘤变(CIN)的诊断中子宫颈电环切除术(LEEP)能否被阴道镜下多点活组织检查(活检)替代。方法:回顾性分析2007年3月以来,因宫颈病变同时行阴道镜下多点活检和LEEP的患者共62例,采用自身对照法,对比研究LEEP与阴道镜下多点活检病理检查结果。结果:LEEP与阴道镜下多点活检的病理检查结果完全相符合者41例,不符合者21例。LEEP术后,因发现早期浸润癌及原位癌行全子宫切除者7例,其余55例患者(宫颈上皮内瘤变患者41例)在LEEP术后密切随访,保留了生育功能,在术后随访的6个月中,无1例出现宫颈细胞学检查异常者。结论:LEEP对CIN的诊断价值是十分重要的,它不能被阴道镜下多点活检所取代。同时,LEEP对CIN有治疗作用。
Objective: To explore whether cervical loop electrocautery (LEEP) can be replaced by colposcopic multipoint biopsy (biopsy) in the diagnosis of cervical intraepithelial neoplasia (CIN). Methods: A retrospective analysis of 62 patients with simultaneous colposcopy biopsy and LEEP due to cervical lesions since March 2007 was performed. The results of LEEP and colposcopy biopsy were compared by self-control method. Results: LEEP and colposcopy multipoint biopsy results of the pathological examination completely consistent with 41 cases, 21 cases did not meet. After LEEP, seven patients with early invasive carcinoma and carcinoma in situ were found to have hysterectomies. The remaining 55 patients (41 patients with cervical intraepithelial neoplasia) were closely followed up after LEEP, and their reproductive functions were retained. During the 6 months of follow-up, none of the patients had abnormal cervical cytology. Conclusion: The diagnostic value of LEEP for CIN is very important. It can not be replaced by colposcopy multipoint biopsy. At the same time, LEEP has a therapeutic effect on CIN.