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目的:探讨肺炎支原体感染与支气管哮喘急性发作的相关性,为支气管哮喘急性发作的治疗提供依据。方法:检测40例哮喘急性发作患儿(观察组)和40例上呼吸道感染患儿(对照组)的外周血肺炎支原体抗体(MP-IgM)及外周血嗜酸性粒细胞计数(EOS),比较两组MP-IgM阳性率和MP-IgM阳性及阴性患者的EOS计数。结果:与对照组比较,观察组MP-IgM阳性率明显升高(χ2=69.832,P=0.0093);MP-IgM阳性患儿的EOS显著高于MP-IgM阴性患儿(t=2.671,P=0.0076)。结论:肺炎支原体感染与支气管哮喘急性发作密切相关,对哮喘急性发作期患儿应常规检测MP-IgM。
Objective: To investigate the relationship between Mycoplasma pneumoniae infection and acute attack of bronchial asthma, and to provide basis for the treatment of acute attack of bronchial asthma. Methods: Peripheral blood serum Mycoplasma pneumoniae antibody (MP-IgM) and peripheral blood eosinophil count (EOS) were detected in 40 children with acute asthma attack (observation group) and 40 children with upper respiratory tract infection (control group) EOS counts were positive for MP-IgM in both groups and in MP-IgM-positive and -negative patients. Results: Compared with the control group, the positive rate of MP-IgM in the observation group was significantly higher (χ2 = 69.832, P = 0.0093); the EOS in MP-IgM positive children was significantly higher than that in MP- = 0.0076). Conclusion: Mycoplasma pneumoniae infection is closely related to the acute attack of bronchial asthma. MP-IgM should be routinely detected in children with acute asthma attack.