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1980年作者曾描述对射出的精子进行减数分裂研究的改良方法.此后,一些实验室利用此方法获得阳性结果.然而,病例的确诊率是低的(5～25%).如果此方法用于常规检测不育男性,其结果如下:(1)与检测的睾丸活检组织的结果相比较,5%的结果非常好;(2)20%的结果是令人满意的;(3)65%的病人可以看到生殖细胞,但多数病人生殖细胞减数分裂停滞,并且全部病人的生殖细胞前期Ⅰ配对异常;(4)约10%病人未发现生殖细胞.上述结果促使作者改进了制备技术,从而获得良好的制备样品,
In 1980, the authors described an improved method of meiosis study of injected sperm, and some laboratories have since obtained positive results using this method. However, the diagnosis rate is low (5-25%). If this method is used The results were as follows: (1) 5% of the results were very good compared to the results of testicular biopsies tested; (2) 20% of the results were satisfactory; (3) 65% Of patients can see the germ cells, but the majority of patients with germ cell meiosis stagnation, and all patients with abnormal pregative Ⅰ pairing; (4) about 10% of patients did not find germ cells.The above results prompted the authors to improve the preparation technology, Thus obtaining a good preparation sample,