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目的分析探讨头孢哌酮治疗细菌性痢疾的临床疗效。方法 110例细菌性痢疾患儿,随机分为对照组和治疗组,各55例。对照组给予氨苄西林治疗,治疗组给予头孢哌酮治疗,对两组患儿的临床疗效进行比较。结果治疗组的退热时间、止泻时间、大镜检转阴时间等临床指标明显优于对照组,差异有统计学意义(P<0.05);治疗组显效43例(78.18%)、有效11例(20.00%)、无效1例(1.82%),总有效率54例(98.18%);对照组显效31例(56.36%)、有效9例(16.36%)、无效15例(27.27%),总有效率40例(72.73%),两组总有效率比较差异有统计学意义(P<0.05)。结论头孢哌酮治疗细菌性痢疾的临床疗效显著,值得临床推广应用。
Objective To investigate the clinical efficacy of cefoperazone in the treatment of bacillary dysentery. Methods 110 cases of children with bacillary dysentery were randomly divided into control group and treatment group, 55 cases each. The control group was given ampicillin, and the treatment group was treated with cefoperazone. The clinical efficacy of the two groups were compared. Results The clinical indexes such as antipyretic time, antidiarrheal time and large microscopic examination negative time in the treatment group were significantly better than those in the control group (P <0.05), and 43 cases (78.18%) in the treatment group were effective and 11 (20.00%), 1 case (1.82%) was ineffective and 54 cases (98.18%) were effective in the control group. The control group was markedly effective in 31 cases (56.36%), effective in 9 cases (16.36%) and ineffective in 15 cases (27.27% The total effective rate was 40 cases (72.73%), the total effective rate was significantly different between the two groups (P <0.05). Conclusion Cefoperazone treatment of bacterial dysentery clinical significant effect, worthy of clinical application.