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目的：探讨综合干预措施对降低口腔癌患者术后下呼吸道感染的效果。方法干预组：某院2012年9月—2013年3月收治的146例口腔癌患者，同期在其围手术期加强实施针对预防下呼吸道感染的综合干预措施；对照组：该院2012年3—8月收治的140例口腔癌患者，执行一般诊疗护理常规，比较两组患者术后下呼吸道感染情况。结果干预组患者术后床头抬高30°、术前术后使用复方洗必泰含漱液口腔护理、全麻喉镜头高压灭菌、全麻气管插管前手卫生以及雾化吸入庆大霉素5项干预措施的执行率均高于对照组，差异均有统计学意义（均P＜0．01）。干预组下呼吸道感染率为0．68％（1例），低于对照组的5．71％（8例），差异有统计学意义（χ2＝4．39，P＜0．05）。结论实施综合干预措施，能有效降低口腔癌患者手术后下呼吸道感染率。“,”Objective To evaluate the effectiveness of comprehensive intervention measures in reducing postopera-tive lower respiratory tract infection (LRTI)in patients with oral cancer.Methods Patients were divided into inter-vention group and control group,intervention group :146 patients who admitted to a hospital between September 2012 and March 2013 received comprehensive intervention measures during perioperative period for preventing post-operative LRTI;control group:140 patients who admitted to the hospital between March and August 2012 received routine medical care,incidence of postoperative LRTI between two groups was compared.Results The implementa-tion rates of 5 intervention measures of intervention group (30° bed head elevation,oral rinse with compound chlo-rhexidine gargle,autoclave sterilization of head of laryngoscope used in general anaesthesia,hand hygiene before anaesthe-sia for endotracheal intubation,and gentamycin inhalation)were all higher than control group (all P<0.01 ). Incidence of LRTI in intervention group was significantly lower than control group ([0.68% ,n= 1]vs [5.71% ,n=8],χ2= 4.39,P<0.05).Conclusion The implementation of comprehensive intervention measures can effectively reduce the incidence of postoperative LRTI in patients with oral cancer.