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5—氟尿嘧啶(代号5—FU),是嘧啶类抗代谢约物,其主要作用是阻碍细胞的核酸合成,即抑制细胞内胸苷酸的生成而阻碍DNA合成,在生殖周期中主要作用于S期,属周期特异性药物,对绒癌、恶性葡萄胎等疗效显著,对其肺转移、消化道转移及泌尿生殖道转移亦有效。作用是使滋养细胞死亡,是滋养细胞肿瘤治疗中的首选药物。但经笔者近年来观察及尝试,5—FU在妇产科的用途不仅止于此,它对子宫颈人乳头瘤病毒感染、输卵管妊娠、植入性胎盘等
5-fluorouracil (code 5-FU) is a pyrimidine antimetabolite, its main role is to hinder cell nucleic acid synthesis, that is, inhibition of intracellular thymidylate production and hinder DNA synthesis in the reproductive cycle, the main role in S Period, is a cycle-specific drugs, on choriocarcinoma, malignant mole and other significant effect on the lung metastasis, digestive tract and genitourinary tract metastasis is also effective. The role is to make trophoblast cell death, is the drug of choice for the treatment of trophoblastic tumors. But in recent years, the author observed and tried, 5-FU in the obstetrics and gynecology use not only stop here, it has cervical HPV infection, tubal pregnancy, placenta accreta