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本文将胃癌患者55例接部位分为贲门、胃底癌组（1例），胃体癌组（1例），胃窦癌组（21例），以非胃癌组33例作为对照。对胃癌组及非胃癌组化疗前及化疗后1、3、5、7天进行血清胃泌素测定。结果表明：化疗前贲门、胃底癌组及胃体癌组血清胃泌素显著升高（P＜0．01），胃窦癌组及非胃癌组血清胃泌素基本在正常范围；化疗后胃癌各组血清胃泌素均有不同程度下降，以第3天后为著（P＜0.01）；非胃癌组化疗前后无明显变化（P＞0.05）。提示：化疗后血清胃泌素的下降为判断胃癌化疗疗效的血清学指标。
In this paper, 55 cases of gastric cancer patients were divided into cardia, gastric fundus cancer group (1 case), gastric cancer group (1 case), gastric antrum cancer group (21 cases), and non-gastric cancer group of 33 cases as a control. Serum gastrin was measured before and after 1, 3, 5, and 7 days after chemotherapy in patients with gastric cancer and non-gastric cancer. The results showed that serum gastrin was significantly elevated in patients with cardia, gastric fundus, and gastric cancer before chemotherapy (P<0.01). Serum gastrin in the gastric antrum cancer group and non-gastric cancer group was basically in the normal range; after chemotherapy Serum gastrin levels in all groups of gastric cancer decreased to varying degrees, with the third day (P<0.01); non-gastric cancer group had no significant changes before and after chemotherapy (P>0.05). Tip: The decrease of serum gastrin after chemotherapy is a serological marker for judging the efficacy of chemotherapy for gastric cancer.