孕妇外周血中存在的微量的胎儿细胞是进行非创伤性产前诊断最理想的样本来源之一。目前常用的分选胎儿细胞方法有流式细胞术、磁激活细胞分离法等 ,其中单细胞分离法的建立是一个新的途径。利用分析胎儿细胞的遗传信息 ,可以进行遗传病的产前诊断 ,如诊断多种染色体病和基因病等 The trace amount of fetal cells present in peripheral blood of pregnant women is one of the most ideal sample sources for non-invasive prenatal diagnosis. The commonly used methods of sorting fetal cells are flow cytometry, magnetic activated cell separation, etc., of which the establishment of single cell isolation method is a new way. The use of genetic information to analyze fetal cells, prenatal diagnosis of genetic diseases, such as the diagnosis of a variety of chromosomal diseases and genetic diseases