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巴塞罗纳市Cotuit Vella区1997年结核病发病率超过160/100 000,是本市主要的结核病高发区。为筛查结核病,对来自该区的415名2岁以上儿童进行结核菌素皮肤试验(TST);发现有27名儿童(6.6％)(95％CI4.5-9.3)已受到感染但未发病。TST阳性率随年龄的增长而明显增加,从2-4岁年龄组的0％到10-14岁年龄组的14.6％。通过对6名TST阳性的儿童进行追踪,新发现了3例培养阳性的成人传染源,其中2人痰涂片阳性。以前接种BCG与结核菌素皮肤试验阳性无关。研究资料支持,对居住在巴塞罗纳市Ciutat Vella区的所有儿童进行TST筛选可作为发现和治疗结核病人的手段。
In 1997, the incidence of tuberculosis in Cotuit Vella district in Barcelona exceeded 160/100 000, making it the main TB prevalence area in the city. To screen for tuberculosis, tuberculin skin test (TST) was performed on 415 children over the age of 2 from the district; 27 children (6.6%) (95% CI 4.5-9.3) were found to have been infected but not affected . The positive rate of TST increased with age, from 0% in 2-4 years old to 14.6% in 10-14 years old. By tracing 6 TST-positive children, 3 newly-infected adults were found, of whom 2 were sputum smear-positive. Previous BCG immunization did not show any positive correlation with tuberculin skin test. Research data support that TST screening of all children living in the Ciutat Vella district of Barcelona can be used as a means of detecting and treating TB patients.