论文部分内容阅读
目的:探讨小儿巨细胞病毒(CMV)肺炎的临床特点、实验室检查及治疗方法。方法:回顾性分析小儿巨细胞病毒肺炎的临床资料。结果:小儿CMV肺炎以小婴儿发病多见,多以咳喘(90.3%)为首发症状就诊,且病程较长,病情较重,多为间质性肺炎,常合并肺外表现,尿荧光定量聚合酶链反应阳性。31例均给与更昔洛韦(GCV)治疗,24例治愈7例好转。结论:小儿CMV肺炎临床表现缺乏特异性;荧光定量聚合酶链反应检测尿液保巨细胞病毒简单蜴插,具有高灵敏性;GCV是治疗婴儿CMV感染的首选药物。
Objective: To investigate the clinical features, laboratory tests and treatment of pediatric cytomegalovirus (CMV) pneumonia. Methods: The clinical data of children with cytomegalovirus pneumonia were retrospectively analyzed. Results: The incidence of CMV pneumonia in infants was more common in young infants. Most of them were treated with cough and asthma (90.3%) as their first symptom. The longer duration and heavier disease were mostly interstitial pneumonia, often associated with extrapulmonary manifestations, and the urinary fluorescence quantitative Polymerase chain reaction positive. 31 cases were treated with ganciclovir (GCV), 24 cases were cured in 7 cases improved. Conclusion: The clinical manifestations of CMV pneumonia in children are not specific. Fluorescent quantitative polymerase chain reaction (PCR) detection of cytochalasin simplex lizards is highly sensitive. GCV is the first choice for the treatment of CMV infection in infants.