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报道了~（２１１）Ａｔ标记抗胃癌单抗３Ｈ１１的高效液相色谱分析方法。采用疏水性色谱柱和梯度洗脱程序，３Ｈ１１紫外色谱峰的保留时间（ｔ＿Ｒ）为１３．００ｍｉｎ，与此相对应出现~（２１１）Ａｔ－３Ｈ１１的放射性色谱峰，并与其它放射性杂质峰有较好的分离。在０．３５～３．５μｇ范围内，３Ｈ１１色谱峰的峰面积与进样量呈线性关系。
A high performance liquid chromatographic method for the detection of ~ (211) At-labeled anti-gastric cancer monoclonal antibody 3H11 has been reported. Using hydrophobic column and gradient elution procedure, the retention time (t_R) of 3H11 UV peak was 13.00 min, which corresponded to the peak of ~ (211) At-3H11 and was consistent with other radioactive impurity peaks Better separation. In the range of 0.35 ~ 3.5μg, the peak area of 3H11 showed a linear relationship with the injection volume.