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对心肌梗塞诊断和掌握病情必须及时,同时应予有效的治疗。本文着重讨论心肌梗塞急性期和慢性期应用阻断药治疗的问题。急性期早期常有穿壁性坏死和伴有缺血。此阶段治疗目的在于缩小梗塞面积,挽救濒死状态的缺血区。β受体阻断药可减少心肌梗塞时交感神经功能亢进所致的耗氧量增加,从而对坏死和缺血区起到良好作用。β受体分为β_1和β_2两类,前者在心肌内、后者在冠状血管内分布。最近已知,在冠状血管中分布有β_1及β_2受体,选择性β_1受体阻断药与冠状血管毫无关系。应用β受体阻断药时冠状血管收缩,血流向缺血区。此外因β受体被阻断,
The diagnosis of myocardial infarction and grasp the condition must be timely, and should be effective treatment. This article focuses on the application of blockade therapy in acute and chronic myocardial infarction. Early acute transversal necrosis often accompanied by ischemia. The purpose of this phase of treatment is to reduce the infarct size and save the ischemic area near the dying condition. β-blockers reduce the increase in oxygen consumption due to sympathetic hyperactivity during myocardial infarction, and thus play a good role in necrosis and ischemia. β receptors are divided into β_1 and β_2 two types, the former in the myocardium, which is distributed in the coronary vessels. It has recently been known that β 1 and β 2 receptors are distributed in coronary vessels, and selective β 1 receptor blockers have nothing to do with coronary blood vessels. Coronary vasoconstriction when applying beta-blocker, blood flow to the ischemic area. In addition because β-receptor is blocked,