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目的探讨高频电波刀(LEEP)术后联合重组人干扰素治疗重型宫颈糜烂的临床疗效。方法选择2009年1月-2010年1月医院收治的重度宫颈糜烂患者,随机分为观察组和对照组;对照组单用LEEP术治疗,而观察组则在LEEP术后加用干扰素-α2a进行治疗;对两组患者的临床疗效和术后宫颈创面愈合率进行比较分析。结果观察组患者的总有效率为97.30%,对照组患者的总有效率为89.19%,两组比较,差异有统计学意义(t=3.86,P<0.05);术后3、6个月的创面治愈率明显提高,差异有统计学意义(P<0.05)。结论 LEEP术后联合重组人干扰素-α2a治疗重型宫颈糜烂具有确切的疗效,在临床上具有广泛的推广应用价值。
Objective To investigate the clinical efficacy of high frequency electrosurgical knife (LEEP) combined with recombinant human interferon in the treatment of severe cervical erosion. Methods The patients with severe cervical erosion treated in our hospital from January 2009 to January 2010 were randomly divided into observation group and control group. The control group was treated with LEEP only, while the observation group was treated with interferon-α2a For treatment; the clinical efficacy of two groups of patients and postoperative cervical wound healing rates were compared. Results The total effective rate was 97.30% in the observation group and 89.19% in the control group. The difference between the two groups was statistically significant (t = 3.86, P <0.05) The wound healing rate was significantly increased, the difference was statistically significant (P <0.05). Conclusion LEEP combined with recombinant human interferon-α2a for the treatment of severe cervical erosion has the exact effect, has a wide range of clinical application value.